regulation 测验

The collected information was stored in a structure formed of pairwise interactions and regulations that includes information about participating components, the origin of publications (PMID) where the interaction was mentioned and a confidence level as an evidence tag from the biocurator.

Because D 1 dopamine receptors are known to act through stimulatory heterotrimeric guanosine triphosphate-binding (G s ) proteins and activation of the cAMP pathway, up-regulation of this pathway in the nucleus accumbens could account for the functional supersensitivity of D 1 receptors observed in these neurons--which occurs in the absence of detectable changes in the receptors themselves--after chronic cocaine (or other stimulant) exposure (18 ).